The condensation device of the cosmetic freeze dryer is an important part of the reproducibility of freeze-dried products (layer temperature, condenser temperature and vacuum degree); and if a power failure occurs and the refrigeration compressor stops, the condenser cannot be cooled, This directly affects the safety of freeze-dried products, especially when a large amount of sublimation occurs in the early stage, which may lead to the scrapping of freeze-dried products, resulting in serious consequences.
Standards to be followed by the condensation device of the cosmetic freeze dryer:
1. The condensing device is used to install the condensing heat exchanger, which is directly connected to the cavity and is isolated from the cavity by the main isolation valve;
2. All surfaces should be self-draining;
3. In the system with anti-steam backflow (for example, to prevent the backflow of steam from the vacuum pump), the condenser should be set at downstream of the steam in the cavity, and the surface of the condenser is not the contact surface with the material, so there is no need to ensure the surface roughness;
4. In the system without steam backflow prevention, the surface of the condenser is the contact surface with the material, and the surface roughness of the condenser should be determined by the user as required.
The plane of the shelf where the product container (such as the vial containing the product) is placed on the shelf of the freeze dryer is the contact surface with the material. If the product is not contained in a container, it is placed directly on the shelf, and the surface of the shelf is the contact surface. The structural component surfaces on the shelves are the contact surfaces. The heat transfer effect between the layers is related to the flatness. Loading/unloading and sealing of containers require the shelves to be level, so the shelves cannot have slopes. In addition to self-draining, there should be other ways to remove the residual CIP liquid, for example, the removable board itself can be heated, and then go through a drying process, or do SIP in a vacuum state, which can remove the shelf surface Purpose of residual CIP liquid. The surface roughness of the shelf should be specified by the user. The user can determine the bottom surface of the shelf according to the process requirements.
The above are the standards that the condensation device of the cosmetic freeze dryer must follow. The condensation device is an important part of the equipment, so users should pay special attention to this part when using it.
