1. The manufacturer's choice
The first choice is a strong freeze dryer manufacturer, which has many years of professional experience and professional technology in the production of freeze dryers, and supports non-standard customization and solutions.
2. Cold trap temperature
The cold trap is a device that is placed between the freeze-drying chamber and the vacuum pump to trap steam. The lower the temperature of the cold trap, the stronger the trap's capture capacity, but the lower the temperature of the cold trap, the higher the requirement for refrigeration, and the machine cost and operating cost are relatively high.
3. Condensation amount
The amount of vapor that the cold trap can capture is related to the total amount of sublimation of water or other solvents in the laboratory's daily experimental operation samples.
4. Ultimate vacuum
The ultimate vacuum degree reflects the leakage of the freeze dryer and the pumping efficiency of the vacuum pump. The vacuum degree of the experiment operation should be within a reasonable range. The vacuum degree is too high, which is not conducive to heat transfer, and the drying speed drops instead.
5. Control and display system
The laboratory series of freeze-drying machines are mainly used for freeze-drying of materials, small batch production and freeze-drying process condition tests.
The control system must have real-time display of freeze-drying process parameters, such as cold trap temperature, vacuum degree, stage time and total process time, etc.; set, modify and effectively execute freeze-drying process procedures; it is recommended to have a communication interface to facilitate data collection and storage .
6. Freeze-drying method and function
Depending on the specific sample, there are different options for freeze-drying. Common laboratory freeze-drying experiments adopt the process b method, that is, freeze-drying in the freeze-drying cavity or hanging bottle freeze-drying. If it is freeze-drying cavity freeze-drying, you need to buy a freeze-drying cavity.And you need to do vial freeze-drying if you choose the capping device. If the bottle is freeze-dried, you need to choose a multi-manifold, which is suitable for round-bottom flasks, wide-mouth filter flasks or ampoules, but you must pay attention to whether you need to choose the corresponding adapter to use in combination.If the user and the samples involved in the test are both lyophilized in the cavity and lyophilized in an external bottle,you can choose a lyophilized cavity with an external hanging port.
Different experiments and different samples have different functional requirements for the freeze dryer. Generally speaking, for the freeze-drying of food, Chinese herbal medicine, powder materials and other samples, it is generally recommended to use a shelf-type freeze dryer; for the operation of vials, you must choose freeze dryer with capping device; it is recommended to use the bottle-hanging method for freeze-drying preservation of microbial strains and be sure to choose the ampoule adapter for freeze-drying; if you want to study the freeze-drying process curve, you must choose the controller to support eutectic point test equipment and software and other working models.
