In-situ Lyophilizer

In-situ lyophilizer

The in-situ lyophilizer adopts separate design of drying chamber and cold trap, using silicone oil as heat conduction medium, which not only saves energy, but also has fast production speed (equipped with electric heat defrost) and convenient cleaning. Automatic plug function can be configured according to test or production requirements. This freeze-drying machine has the advantages of flexible structure, excellent performance, energy saving and environmental protection, which can meet the requirements of most experiments and pilot production.

The basic principle of freeze-drying is based on the change of three states of water. Water has three states: solid, liquid and gas, which can be transformed and coexist. When water is at the triple point (temperature of 0.01 ° C, vapor pressure of 610.5 Pa), water, ice, and steam can coexist and balance each other. Under the condition of high vacuum, using the sublimation principle, the water in the pre-frozen material can be directly sublimated into water vapor without melting ice, so as to achieve the purpose of freeze-drying.

What are the advantages and characteristics of in situ lyophilizer?

1, many heat sensitive substances will not occur denaturation or deactivation. Some of the volatile components in the material are lost very little when dried at low temperatures.

2. In the process of lyophilization, the growth of microorganisms and the action of enzymes cannot be carried out, so the original characteristics can be maintained.

3. Due to the drying in the frozen state, the volume is almost unchanged, and the original structure is kept, so the concentration phenomenon will not occur.

4. Because the water in the material exists in the form of ice crystals after pre-freezing, the inorganic salts dissolved in the water are evenly distributed in the material. In the process of sublimation, the dissolved substances dissolved in water will precipitate, avoiding the phenomenon of surface hardening caused by the precipitation of inorganic salts on the surface due to the internal water migration to the surface in the general drying method.

5. The material dried by the in-situ lyophilizer is loose and porous, spongy, and dissolved quickly and completely after adding water, almost immediately restoring the original character.

6. Because the drying is carried out under a vacuum, there is little oxygen, so some easily oxidized substances are protected.

7. Drying can eliminate more than 95% ~ 99% of the moisture, so that the dried products can be stored for a long time without deterioration.

8, because the material is frozen, the temperature is very low, so the heat source temperature is not high, the use of normal temperature or low temperature heater can meet the requirements. If the freezer and the drying chamber are separated, the drying chamber does not need insulation, and there will be no great heat loss, so the use of heat is very economical.

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With strong technical background and rich customer service experience ,  Kassel is committed to providing customers with high-quality machinery at favorable prices. The product has stable performance, high precision, safety and durability, which can help customers improve product yield, reduce production costs, and improve market competitiveness.

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