Working Principle Of Biological Lyophilization Dryer
Working principle of biological lyophilization dryer
Biopharmaceutical working principle of the lyophilizer is biological products to precool crystallization in the frozen vacuum drying machine, and then vacuum sublimation drying process, the whole process must be biological products freezing dryer running under strict control, freeze drier including enclosure, cooling system, heating system, vacuum system, circulatory system and control system, Biopharmaceutical freeze-drying is carried out by means of a freeze-drying machine combined with a mature process formula.
Biological products freeze drying machine according to the characteristics of various biological products requirements, cooperate with corresponding freeze-drying technology processing, make the products physical structure remains unchanged, the chemical structure changes is very small, biological products, keep the original solid structure and form in the process of sublimation drying, distillation solid ice into water vapor in the products after leaving pore, formed peculiar spongy porous structure, It has ideal instant solubility and nearly complete rehydration. Because the working principle of biopharmaceutical lyophilizer is the drying process of freeze vacuum drying in extremely low temperature and high vacuum conditions, so the thermal denaturation of biological products is small, which can ensure the biological activity of products to the maximum extent.
Biological products in the sublimation process of the lyophilizer system temperature control at a lower temperature state, so for those who are not resistant to 1% heat, such as enzymes, hormones, proteins, nucleic acids, antibiotics, blood and immune products and other heat-sensitive biological products and biological tissue drying is particularly suitable. More than 97%~99% moisture can be removed by freeze-drying, which is beneficial to the long-term preservation of biological materials. The drying process of biological products is carried out under vacuum conditions, so it is not easy to oxidize. Because some biological products have special chemical, physical and biological instability, the major biological enterprises through the working principle of biological pharmaceutical freeze-drying machine, the freeze-drying technology of biological products freeze-drying machine is widely used in the processing of biological products.
Parameter:
Model | KFD-20 | KFD-25 | KFD-30 | KFD-50 | KFD-100 |
Tray area(m²) | 20 | 25 | 30 | 50 | 100 |
Input capacity(kg/batch) | 200 | 250 | 300 | 500 | 1000 |
Min. cold trap temperature(℃) | <-45℃ | <-45℃ | <-45℃ | <-45℃ | <-45℃ |
Vacuum degree(pa) | <10pa | <10pa | <10pa | <10pa | <10pa |
Tray temp. | -35~+100℃ | -35~+100℃ | -35~+100℃ | -35~+100℃ | -35~+100℃ |
Tray quantity | 18 | 22 | 18 | 28 | 36 |
Tray Size(mm) | 2200x600 | 2200x600 | 3300x600 | 3300x600 | 5000x600 |
Cooling method | Water cooled | Water cooled | Water cooled | Water cooled | Water cooled |
Total power(kw) | 45 | 50 | 60 | 100 | 180 |
Total weight(kg) | 8000 | 9000 | 11000 | 20000 | 40000 |
Pre-sale:
As soon as we get your inquiry, we will always reply to your email on time and try our best to recommend you the most suitable freeze dryer. Detailed tech-info will also be provided for you.
After-sale:
We will keep in touch with you, to make sure every parts of the freeze dryer work well. One year warranty, free online service.
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