Large Pharmaceutical Freeze Drying Equipment
Working principle of pharmaceutical freeze dryer equipment
The working principle of the pharmaceutical freeze dryer equipment (pharmaceutical freeze dryer) under the action of low temperature, the solution in the medicine is rapidly frozen, and then sublimated and dried under vacuum conditions, and at the same time, the ice crystal problem generated at this time is removed and then decomposed Function to remove the moisture present in the medicine, and finally get the dry medicine. The application of freeze-drying technology of medicines is a work link from medicine preparation, pre-freezing, sublimation, absorption, drying, and sealing.
The pharmaceutical freeze dryer, as the most critical link in drug production at present, contributes to drug stability. In the production of medicines, the medicinal properties under freezing conditions are stable, avoiding the loss of medicinal effect caused by the imbalance of the medicine. After the medicine is dried, although its volume is reduced and changed to a certain extent, its color, shape and composition are basically unchanged, which avoids the phenomenon of concentration. At present, pharmaceutical freeze dryers are used in the pharmaceutical industry for biological products, chemicals, natural medicines, heat-sensitive drugs, antibiotics, freeze-dried injections, freeze-drying of raw material intermediates, oral freeze-dried tablets, freeze-dried capsules, etc.
Common problems and Solutions
1.High pressure, high pressure alarm
(1) There are too many refrigerants and the exhaust pressure is high. Some refrigerant should be discharged.
(2) The cooling water temperature is high, the flow is insufficient or the water condenser is scaling.
(3) There is leakage in the low pressure section of refrigeration pipeline, and air is inhaled.
(4) High pressure exhaust valve is not fully opened or damaged, resulting in poor exhaust.
It can be reset by the alarm elimination reset button, and the button switch is on the high pressure relay.
2.Oil pressure difference alarm
(1) The oil return is not smooth, resulting in insufficient oil level in the crankcase of the compressor, and the oil pump cannot absorb oil. Generally, it is necessary to replace the oil separator.
(2) The oil is dirty, causing the oil pump filter to be blocked. It is necessary to change the oil and clean the oil filter.
(3) Oil pressure differential relay failed. Replace the oil pressure differential relay with a new one.
(4) The oil pump is out of order. Replace the oil pump with a new one.
(5) Refrigeration system evaporation is not good, there is refrigerant into the crankcase. The refrigerant oil is brought into the system, resulting in low oil pressure. Turn down the liquid supply valve at the outlet of the condenser or adjust the thermal expansion valve (increase the superheat of the system). After the compressor starts 90 s, the oil pressure differential relay will work. If there is no oil pressure difference, it will alarm. After the alarm, the alarm can be eliminated through the reset button on the oil pressure difference relay.
FAQ
Q1：How long can I expect to get the sample?
A:We will send the sample to you within 30 days after confirming your need,he arrival time depends on our distance.
Q2:What's the method of packaging & shipping?
A:Export Wooden case&FOB Shanghai.
Q3:What about the lead time for mass production?
A:30 work days from date of contract signing (down payment).
Q4:What are your main products?
A:Mould temperature control unit, oil and water TCU,chiller ,freeze dryer,mold cleaner.
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